Hepatitis C - mode of transmission clinical features complications and managementInfection due to hepatitis c virus is another cause of chronic hepatitis. Like hepatitis B virus this virus is transmitted through contaminated blood products, sexual contact and use of contaminated needles which is common among drug addicts. Hence those who require repeated blood transfusion or transfusion of blood products like patients of thalassemia and hemophilia are at increases risk. . Vertical transmission from an infected pregnant woman to her fetus can also occur. It is unlikely to be transmitted through breast milk. Symptoms and signs: The incubation period varies from one to five months. The disease has a very gradual onset with nonspecific symptoms like fever, chronic fatigue or abdominal discomfort. Jaundice may not be visible in many patients. Liver may be enlarged.
Laboratory investigations: The liver enzymes are elevated end their levels fluctuate over a period of time. Diagnosis can be confirmed by demonstrating anti HCV antibodies. It is also possible to detect the RNA of the virus using specialized tests. Liver biopsy is performed in chronic hepatitis to detect scarring-a condition called cirrhosis. Treatment is not very satisfactory. Interferon with or without an antiviral drug ribavirin is being tried. Relapses are common. Useful links
Page last reviewed on 8th November 2009
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